Yoda 1

CAS No. : 448947-81-7

MCE 国际站：Yoda 1

产品活性：Yoda 1 是一种有效的选择性 Piezo1 激动剂。Yoda 1 激活纯化的 Piezo1 通道。Yoda 1 能有效抑制表皮生长因子 (EGF) 诱导的巨胞饮。Yoda 1 增强 Ca²⁺ 内流，随后激活钙激活钾通道 KCa3.1 和抑制 Rac1 激活。

研究领域：Membrane Transporter/Ion Channel  |  PI3K/Akt/mTOR  |  MAPK/ERK Pathway  |  Stem Cell/Wnt

作用靶点：Piezo Channel  |  Akt  |  ERK  |  Potassium Channel

In Vitro: Yoda1 (0-6 μM, 5 min) induces the activation of both Akt and ERK1/2, which is not dependent on Piezo1.
Yoda1 (1.5 μM, 5 min) inhibits Rac1 activation.

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